Orthoherpesviridae · Lymphocryptovirus
| Acyclovir | EBV | Viral DNA polymerase inhibitor | Approved (other) | JapanChinaRussia | Viral DNA pol | |
| Artesunate | EBV | Unclear | Preclinical | — | Unknown | |
| Brincidofovir | EBV | Viral DNA polymerase inhibitor | Phase 3 | — | Viral DNA pol | |
| Camptothecin | EBV | Topoisomerase I inhibitor | Preclinical | — | Human topoisomerase | |
| Chlorpromazine | EBV | Inhibits assembly of clathrin-coated pits at the plasma membrane | Preclinical | — | Human (multiple) | |
| Cidofovir | EBV | Viral DNA polymerase inhibitor | Preclinical | — | Viral DNA pol | |
| Emodin | EBV | — | Preclinical | — | Human (multiple) | |
| Fiacitabine | EBV | Inhibits viral DNA synthesis | Preclinical | — | Viral DNA pol | |
| Filociclovir | EBV | Dual DNA polymerase/kinase inhibitor; Nucleoside analog | Preclinical | — | Viral DNA pol | |
| Foscarnet | EBV | Pyrophosphate analog DNA polymerase inhibitor | Approved (other) | Japan | Viral DNA pol | |
| Ganciclovir | EBV | Viral RNA polymerase inhibitor | Approved (other) | JapanChina | Viral DNA pol | |
| Glycyrrhizin | EBV | — | Preclinical | — | Human TNF | |
| Leflunomide | EBV | Pyrimidine synthesis inhibitor | Preclinical | — | Human DHODH | |
| Luteolin | EBV | Unknown | Preclinical | — | Unknown | |
| Niclosamide | EBV | — | Preclinical | — | Human (multiple) | |
| Novobiocin | EBV | Bacterial DNA gyrase inhibitor (targeting GyrB) | Preclinical | — | Unknown | |
| Promethazine | EBV | Inhibits assembly of clathrin-coated pits at the plasma membrane | Preclinical | — | Human ion channel | |
| Resveratrol | EBV | Multiple | Preclinical | — | Human multiple; Viral transcriptional regulator | |
| Seliciclib | EBV | Cyclin-dependent kinase (CDK) inhibitor | Preclinical | — | Human PTK | |
| Teriflunomide | EBV | — | Preclinical | — | Human DHODH | |
| Valacyclovir | EBV | Nucleoside analog DNA polymerase enzyme inhibitor; L-valine ester of aciclovir. | FDA approved | FDAJapanChinaRussia | Viral DNA pol | |
| Valproic Acid | EBV | HDAC inhibitor | Preclinical | — | Human HDAC | |
| Verdinexor | EBV | Nuclear export inhibitor | Preclinical | — | Human exportin | |
| Zidovudine | EBV | Inhibition of viral RT | Approved (other) | JapanRussia | Viral DNA pol |