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Fiacitabine

Inhibits viral DNA synthesis

2D Structure

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3D Structure

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Chemical Identifiers

C1=C(C(=NC(=O)N1C2C(C(C(O2)CO)O)F)N)I
GIMSJJHKKXRFGV-BYPJNBLXSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus7

Human alphaherpesvirus 3
VZV
Target: Viral DNA pol
Phase 2
Preclinical
Phase 2
Phase 3
Approved
PMID:3525694
Human betaherpesvirus 5
CMV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:3525694
Hepatitis B virus
HBV
Target: Viral RT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:1629711
Human alphaherpesvirus 1
HSV-1
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:6273355
Human alphaherpesvirus 2
HSV-2
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:3015003
Human gammaherpesvirus 4
EBV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:25267682
Human gammaherpesvirus 8
KSHV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:25267682