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Niclosamide

inhibiting oxidative phosphorylation · Unknown

2D Structure

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3D Structure

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Chemical Identifiers

C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O
RJMUSRYZPJIFPJ-UHFFFAOYSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus17

Phase 3
Preclinical
Phase 2uncertain
Phase 3
Approved
Phase 2 ref (PMID:35138402) Phase 3 ref (nature.com) NCT04603924
Dengue virus
DENV-2
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30125275
Zika virus
ZIKV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27571349 PMID:29378701
Chikungunya virus
CHIKV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27742486
Zaire ebolavirus
EBOV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30700611
Human gammaherpesvirus 4
EBV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27939840
Human alphaherpesvirus 1
HSV-1
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
Human alphaherpesvirus 2
HSV-2
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Ref
Japanese encephalitis virus
JEV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24348901
Lassa mammarenavirus
LASV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30700611
Rabies lyssavirus
RABV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:15215127
Sindbis virus
SINV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
Vaccinia virus
VACV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
Indiana vesiculovirus
VSV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
Human orthopneumovirus
RSV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:33476693
Lujo mammarenavirus
LUJV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:34203149