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Verdinexor

Nuclear export inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

C1=CC=NC(=C1)NNC(=O)C=CN2C=NC(=N2)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F
OPAKEJZFFCECPN-XQRVVYSFSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus10

Human mastadenovirus C
HAdV-5
Target: Human exportin
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30332435
Human polyomavirus 1
BKV
Target: Human exportin
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30332435
Human betaherpesvirus 5
CMV
Target: Human exportin
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30332435
Human gammaherpesvirus 4
EBV
Target: Human exportin
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30332435
Alphapapillomavirus 10
HPV-11
Target: Human exportin
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30332435
Alphapapillomavirus 7
HPV-18
Target: Human exportin
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30332435
Human polyomavirus 2
JCV
Target: Human exportin
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30332435
Human gammaherpesvirus 8
KSHV
Target: Human exportin
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30332435
Influenza A virus
FLUAV
Target: Human exportin
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27893810
Human orthopneumovirus
RSV
Target: Human exportin
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30541831