RaDVaC Data Explorer
Antiviral database
Virus Taxonomy
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Cidofovir
Viral DNA polymerase inhibitor
2D Structure
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3D Structure
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Chemical Identifiers
SMILES:
C1=CN(C(=O)N=C1N)CC(CO)OCP(=O)(O)O.O.O
InChI Key:
FPKARFMSZDBYQF-ILKKLZGPSA-N
PubChem
DrugBank
ClinicalTrials.gov
PubMed
Clinical Development by Virus
15
Human betaherpesvirus 5
CMV
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2
unknown
Phase 3
Approved
FDA
Phase 2 ref (PMID:9036798)
Phase 3 ref (pubmed.ncbi.nlm.nih.gov)
PubChem CID:60613
NCT01866397
DB00369
Human cytomegalovirus (HCMV)
HCMV
Target: DNA polymerase UL54
FDA approved
Preclinical
Phase 2
positive
Phase 3
positive
Approved
FDA
Approval ref: AntiviralDb
Human polyomavirus 1
BKV
Target: Viral DNA pol
Phase 2
Preclinical
Phase 2
Phase 3
Approved
NCT00138424
Human alphaherpesvirus 1
HSV-1
Target: Viral DNA pol
Phase 2
Preclinical
Phase 2
Phase 3
Approved
NCT00002116
NCT01610765
Human alphaherpesvirus 2
HSV-2
Target: Viral DNA pol
Phase 2
Preclinical
Phase 2
Phase 3
Approved
NCT00002116
NCT01610765
Human papillomavirus
HPV
Target: Viral DNA pol
Phase 2
Preclinical
Phase 2
Phase 3
Approved
NCT00550589
Human mastadenovirus C
HAdV-5
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30287226
Primate erythroparvovirus 1
B19V
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:25446336
Human gammaherpesvirus 4
EBV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30287227
Hepacivirus C
HCV
Target: Viral RNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Ref
Human betaherpesvirus 6
HHV-6
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30287227
Human polyomavirus 2
JCV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30287227
Human gammaherpesvirus 8
KSHV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30287227
Molluscum contagiosum virus
MCV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:21994641
Human alphaherpesvirus 3
VZV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30287226