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Zidovudine

Inhibition of viral RT

2D Structure

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3D Structure

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Chemical Identifiers

CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]
HBOMLICNUCNMMY-XLPZGREQSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus6

FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanRussia
Approval ref: AntiviralDbApproval ref (pmda.go.jp)
Human immunodeficiency virus 1
HIV-1
Target: Viral RT
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanRussia
Approval ref (pmda.go.jp) DB00495
Zaire ebolavirus
EBOV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanRussia
Approval ref (pmda.go.jp) PMID:27902714
Human gammaherpesvirus 4
EBV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanRussia
Approval ref (pmda.go.jp) PMID:2834997
Human alphaherpesvirus 1
HSV-1
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanRussia
Approval ref (pmda.go.jp) PMID:32096195
Hantaan orthohantavirus
HTNV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:18459839