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Acyclovir

Viral DNA polymerase inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

C1=NC2=C(N1COCCO)NC(=NC2=O)N
MKUXAQIIEYXACX-UHFFFAOYSA-N

Clinical Development by Virus8

Human alphaherpesvirus 2
HSV-2
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChinaRussia
Human alphaherpesvirus 3
VZV
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChinaRussia
Human alphaherpesvirus 1
HSV-1
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2
Phase 3
Approved
FDAJapanChinaRussia
Alphapapillomavirus 10
HPV-6
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Alphapapillomavirus 10
HPV-11
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Human betaherpesvirus 5
CMV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChinaRussia
Human gammaherpesvirus 4
EBV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChinaRussia
Human betaherpesvirus 6
HHV-6
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChinaRussia