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Filociclovir

Dual DNA polymerase/kinase inhibitor; Nucleoside analog

2D Structure

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3D Structure

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Chemical Identifiers

C1C(=CN2C=NC3=C2NC(=NC3=O)N)C1(CO)CO
KMUNHOKTIVSFRA-KXFIGUGUSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus5

Human betaherpesvirus 5
CMV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
NCT01433835
Human mastadenovirus C
HAdV-5
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30287226
Human gammaherpesvirus 4
EBV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30287227
Human betaherpesvirus 6
HHV-6
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30287227
Human gammaherpesvirus 8
KSHV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30287227