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Ganciclovir

Viral RNA polymerase inhibitor · CDK inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N
IRSCQMHQWWYFCW-UHFFFAOYSA-N
PubChemDrugBankClinicalTrials.govPubMed

Clinical Development by Virus10

Human betaherpesvirus 5
CMV
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2unknown
Phase 3
Approved
FDAJapanChina
Phase 2 ref (PMID:25304390) Phase 3 ref (Ref) Approval ref: AntiviralDbApproval ref (pmda.go.jp) PubChem CID:135398740 DB01004 NCT02943057
Human mastadenovirus D
HAdV-22
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2unknown
Phase 3
Approved
JapanChina
Phase 2 ref (PMID:21660226) Phase 3 ref (researchgate.net) Approval ref (pmda.go.jp) PMID:30677427 NCT01533480
Human alphaherpesvirus 3
VZV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChina
Approval ref (pmda.go.jp) PMID:30677427 NCT02382588
Hepatitis B virus
HBV
Target: Viral RT
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChina
Approval ref (pmda.go.jp) PMID:9407355
Human mastadenovirus C
HAdV-2
Target: Human PTK
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChina
Approval ref (pmda.go.jp) PMID:30677427
Human mastadenovirus D
HAdV-19
Target: Human PTK
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChina
Approval ref (pmda.go.jp) PMID:30677427
Human gammaherpesvirus 4
EBV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChina
Approval ref (pmda.go.jp) PMID:30677427
Human alphaherpesvirus 1
HSV-1
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChina
Approval ref (pmda.go.jp) PMID:30287226
Human alphaherpesvirus 2
HSV-2
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChina
Approval ref (pmda.go.jp) PMID:30287226
Vaccinia virus
VACV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChina
Approval ref (pmda.go.jp) PMID:30677427