Approved and Investigational Antivirals

Data updated: 5/14/2026
355
Unique Drugs
157
Target Viruses
1,638
Drug-Virus Pairs
173
FDA Approved
1,638 results
nirmatrelvirSARS-CoV-2Protease inhibitor
FDA approved
FDAJapanChina
Viral protease
kegg.jppmda.go.jp
Acetylsalicylic acidSARS-CoV-2Cyclooxygenase inhibitor, inhibiting the NF-κB pathway
Phase 3
—Human COX
thelancet.comNCT04808895
AcyclovirHSV-2Viral DNA polymerase inhibitor
FDA approved
FDAJapanChinaRussia
Viral DNA pol
AntiviralDbpmda.go.jppubmed.ncbi.nlm.nih.gov
AcyclovirVZVViral DNA polymerase inhibitor
FDA approved
FDAJapanChinaRussia
Viral DNA pol
AntiviralDbpmda.go.jpRef
AlisporivirHCV—
Phase 3
—Human CYPs
pubmed.ncbi.nlm.nih.govPMID:26118427NCT02753699
ArtesunateCMVUnclear
Phase 3
—Unknown
pubmed.ncbi.nlm.nih.govPMID:23827788NCT00284687
AzithromycinRSV—
Phase 3
—Human (multiple)
researchgate.netRefNCT02911935
AzithromycinSARS-CoV-2—
Phase 3
—Human (multiple)
RefPMID:33676597
BrincidofovirHSV-1Viral DNA polymerase inhibitor
Phase 3
—Viral DNA pol
pubmed.ncbi.nlm.nih.govPMID:28197698PMID:30120866
BrincidofovirBKVViral DNA polymerase inhibitor
Phase 3
—Viral DNA pol
pubmed.ncbi.nlm.nih.govNCT01769170
BrincidofovirVACVViral DNA polymerase inhibitor
Phase 3
—Viral DNA pol
pubmed.ncbi.nlm.nih.govPMID:30677427NCT01143181
BrincidofovirHAdVViral DNA polymerase inhibitor
Phase 3
—Viral DNA pol
RefNCT02087306NCT01143181
BrincidofovirCMVViral DNA polymerase inhibitor
Phase 3
—Viral DNA pol
pmc.ncbi.nlm.nih.govNCT01769170NCT01143181
BrincidofovirHHV-6Viral DNA polymerase inhibitor
Phase 3
—Viral DNA pol
PMID:32076716NCT01769170
CidofovirCMVViral DNA polymerase inhibitor
FDA approved
FDA
Viral DNA pol
pubmed.ncbi.nlm.nih.govPMID:9036798PubChem CID:60613
CyclosporineHCVCalcineurin inhibitor; allows for inhibition of T cell activation
Phase 3
—Human CYPs
pubmed.ncbi.nlm.nih.govPMID:20112171PMID:16382464
EzetimibeHCVIntestinal cholesterol and related phytosterol absorption inhibitor
Phase 3
—Human cholesterol transporter
RefNCT02971033NCT02768545
FoscarnetCMVPyrophosphate analog DNA polymerase inhibitor
FDA approved
FDAJapan
Viral DNA pol
AntiviralDbpmda.go.jpRef
GanciclovirCMVViral RNA polymerase inhibitor
FDA approved
FDAJapanChina
Viral DNA pol
AntiviralDbpmda.go.jpRef
GanciclovirHAdV-22Viral RNA polymerase inhibitor
Approved (other)
JapanChina
Viral DNA pol
pmda.go.jpresearchgate.netPMID:21660226
ImatinibSARS-CoV-2Abl; Kit; PDGFRB inhibitor
Phase 3
—Human PTK
ccforum.biomedcentral.comPMID:36639911NCT04394416
InosineHIV-1Stimulates cell-mediated immune response
Preclinical
—Viral RT
link.springer.comPMID:1693173PMID:7520643
IvermectinDENVImportin ?/?-mediated nuclear import inhibitor
Phase 3
—Human importin
PMID:33462580NCT03432442NCT02045069
LopinavirHIV-1HIV protease inhibitor
FDA approved
FDAJapanRussia
Viral protease
kegg.jppmda.go.jpaccessdata.fda.gov
LopinavirHIV-2HIV protease inhibitor
FDA approved
FDAJapanRussia
Viral protease
kegg.jppmda.go.jpaccessdata.fda.gov
Showing 1 to 25 of 1,638 results
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