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Lopinavir

HIV protease inhibitor

2D Structure

Could not render structureView on PubChem

3D Structure

No structure available on PubChemSearch PubChem

Chemical Identifiers

CC1=C(C(=CC=C1)C)OCC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)NC(=O)C(C(C)…
KJHKTHWMRKYKJE-SUGCFTRWSA-N
PubChemDrugBankClinicalTrials.govPubMed

Clinical Development by Virus6

Human immunodeficiency virus 1
HIV-1
Target: Viral protease
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanRussia
Phase 3 ref (accessdata.fda.gov) Approval ref (kegg.jp) Approval ref (pmda.go.jp) PubChem CID:92727 DB01601 NCT01772940
Human immunodeficiency virus 2
HIV-2
Target: Viral protease
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanRussia
Phase 3 ref (accessdata.fda.gov) Approval ref (kegg.jp) Approval ref (pmda.go.jp) PubChem CID:92727 DB01601 NCT02150993
Approved (other)
Preclinical
Phase 2positive
Phase 3
Approved
Japan
Phase 2 ref (PMID:33026741) Approval ref (kegg.jp) Approval ref (pmda.go.jp) NCT02845843
Zika virus
ZIKV
Target: Viral protease
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28712942
Human metapneumovirus
HMPV
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) Ref
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:32251767