Retroviridae · Lentivirus
| Inosine | HIV-1 | Stimulates cell-mediated immune response | Preclinical | — | Viral RT | |
| Lopinavir | HIV-1 | HIV protease inhibitor | FDA approved | FDAJapanRussia | Viral protease | |
| Nelfinavir | HIV-1 | HIV protease inhibitor | FDA approved | FDAJapan | Viral protease | |
| Ritonavir | HIV-1 | HIV protease inhibitor | FDA approved | FDAJapanRussia | Viral protease | |
| Tenofovir | HIV-1 | Nucleotide analog RT inhibitor | FDA approved | FDAChinaRussia | Viral RT | |
| RDEA806 | HIV-1 | — | Phase 2 | — | — | |
| islatravir | HIV-1 | — | Phase 2 | — | — | |
| GSK2838232 | HIV-1 | — | Phase 2 | — | — | |
| cobicistat | HIV-1 | — | Approved (other) | Japan | — | |
| vorinostat | HIV-1 | — | Phase 2 | — | — | |
| romidepsin | HIV-1 | — | Phase 2 | — | — | |
| AMD11070 | HIV-1 | — | Phase 2 | — | — | |
| Methotrexate | HIV-1 | — | Phase 2 | — | — | |
| amdoxovir | HIV-1 | — | Phase 2 | — | — | |
| GSK3640254 | HIV-1 | — | Phase 2 | — | — | |
| GSK3532795 | HIV-1 | — | Phase 2 | — | — | |
| Tenofovir disoproxil | HIV-1 | — | FDA approved | FDAJapanChina | — | |
| Adefovir dipivoxil | HIV-1 | — | FDA approved | FDAJapan | — | |
| Lenacapavir | HIV-1 | — | FDA approved | FDAEMAJapan | — | |
| Adefovir | HIV-1 | Inhibits viral DNA synthesis | Phase 2 | — | Viral RT | |
| Alisporivir | HIV-1 | — | Preclinical | — | Human CYPs | |
| Amprenavir | HIV-1 | Protease inhibitor | FDA approved | FDAJapan | Viral protease | |
| Atazanavir | HIV-1 | Protease inhibitor | FDA approved | FDAJapanRussia | Viral protease | |
| Azacitidine | HIV-1 | Nucleoside analog DNA methyl transferase inhibitor | Preclinical | — | Viral RT | |
| Azithromycin | HIV-1 | — | Preclinical | — | Human (multiple) |