Rift Valley fever phlebovirus
| Azacitidine | RVFV | Nucleoside analog DNA methyl transferase inhibitor | Preclinical | — | Viral RNA pol | |
| Bortezomib | RVFV | Proteasome inhibitor (26S subunit) | Preclinical | — | Human proteasome | |
| Cyclosporine | RVFV | Calcineurin inhibitor; allows for inhibition of T cell activation | Preclinical | — | Human CYPs | |
| Emetine | RVFV | — | Preclinical | — | Human ribosome | |
| Ezetimibe | RVFV | Intestinal cholesterol and related phytosterol absorption inhibitor | Preclinical | — | Human cholesterol transporter | |
| Favipiravir | RVFV | Viral RNA polymerase inhibitor | Approved (other) | Japan | Viral RNA pol | |
| Galidesivir | RVFV | RNA-dependent RNA polymerase (RdRp) inhibitor | Preclinical | — | Viral RNA pol | |
| Minocycline | RVFV | Bacterial protein synthesis inhibitor by binding with the 30S ribosomal subunit. | Preclinical | — | Human (multiple) | |
| Monensin | RVFV | — | Preclinical | — | Unknown | |
| Obatoclax | RVFV | Bcl-2 family inhibitor | Preclinical | — | Human MCL1 | |
| Oritavancin | RVFV | Transglycosylation; transpeptidation and cell membrane interaction/disruption inhibitor | Preclinical | — | Unknown | |
| Ritonavir | RVFV | HIV protease inhibitor | Approved (other) | JapanRussia | Unknown | |
| Sirolimus | RVFV | IL-2-dependent T-cell proliferation inhibitor | Preclinical | — | Human PTK | |
| Suramin | RVFV | Unclear | Preclinical | — | Human (multiple) | |
| Thioridazine | RVFV | Prevent viral entry | Preclinical | — | Human ion channel |