RaDVaC Data Explorer
Antiviral database
Virus Taxonomy
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Obatoclax
Bcl-2 family inhibitor
2D Structure
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3D Structure
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Chemical Identifiers
SMILES:
CC1=CC(=C(N1)C=C2C(=CC(=C3C=C4C=CC=CC4=N3)N2)OC)C
InChI Key:
RFTSSZJZXOSICM-GRSHGNNSSA-N
ClinicalTrials.gov
PubMed
Clinical Development by Virus
14
Lymphocytic choriomeningitis mammarenavirus
LCMV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:31302150
Severe acute respiratory syndrome-related coronavirus
SARS-CoV-2
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:33670363
PMID:34586865
Influenza A virus
FLUAV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:22910914
Enterovirus B
ECHOV-1
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:31635418
Human metapneumovirus
HMPV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Ref
Human alphaherpesvirus 2
HSV-2
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Ref
Argentinian mammarenavirus
JUNV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:31302150
Lassa mammarenavirus
LASV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:31302150
Rift Valley fever phlebovirus
RVFV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Ref
Sindbis virus
SINV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:22910914
West Nile virus
WNV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27993855
Yellow fever virus
YFV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27993855
Zika virus
ZIKV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:28049006
Lujo mammarenavirus
LUJV
Target: Human MCL1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:34203149