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Ritonavir

HIV protease inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

CC(C)C1=NC(=CS1)CN(C)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=CC=C2)CC(C(CC3=CC=CC…
NCDNCNXCDXHOMX-XGKFQTDJSA-N
PubChemDrugBankClinicalTrials.govPubMed

Clinical Development by Virus6

Human immunodeficiency virus 1
HIV-1
Target: Viral protease
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanRussia
Phase 3 ref (clinicalinfo.hiv.gov) Approval ref: AntiviralDbApproval ref (kegg.jp) Approval ref (pmda.go.jp) PubChem CID:392622 DB00503 NCT01702090
Human immunodeficiency virus 2
HIV-2
Target: Viral protease
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanRussia
Phase 3 ref (clinicalinfo.hiv.gov) Approval ref (kegg.jp) Approval ref (pmda.go.jp) PubChem CID:392622 NCT02150993
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanRussia
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:26198719 NCT02150993
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanRussia
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:33260064
Zaire ebolavirus
EBOV
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanRussia
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:29920098
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanRussia
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:29698664