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Favipiravir

Viral RNA polymerase inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

C1=C(N=C(C(=O)N1)C(=O)N)F
ZCGNOVWYSGBHAU-UHFFFAOYSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus20

Influenza virus
Influenza
Target: RNA polymerase
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChinaRussia
Approval ref: AntiviralDbApproval ref (kegg.jp) Approval ref (pmda.go.jp)
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
JapanChinaRussia
Approval ref (kegg.jp) Approval ref (pmda.go.jp) NCT04359615
Influenza A virus
FLUAV
Target: Viral RNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChinaRussia
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PubChem CID:492405 NCT03394209
Influenza B virus
FLUBV
Target: Viral RNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChinaRussia
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PubChem CID:492405 NCT03394209
Influenza C virus
FLUCV
Target: Viral RNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChinaRussia
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PubChem CID:492405 NCT03394209
Zaire ebolavirus
EBOV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) NCT02329054
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:29936152
Chikungunya virus
CHIKV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28958920
Marburg marburgvirus
MARV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:29369776
Andes orthohantavirus
ANDV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:23856782
Mamastrovirus 9
Ast-VA1
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:31864069
Lassa mammarenavirus
LASV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:29882740
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:31302150
Nipah henipavirus
NiV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:29765101
Rabies lyssavirus
RABV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:29459063
Rift Valley fever phlebovirus
RVFV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:19428599
Sin Nombre orthohantavirus
SNV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:23856782
Yellow fever virus
YFV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:19428599
Zika virus
ZIKV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:29967017
Lujo mammarenavirus
LUJV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:34203149