RaDVaC Data Explorer
Antiviral database
Virus Taxonomy
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Tenofovir
Nucleotide analog RT inhibitor
2D Structure
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3D Structure
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Chemical Identifiers
SMILES:
CC(CN1C=NC2=C(N=CN=C21)N)OCP(=O)(O)O
InChI Key:
SGOIRFVFHAKUTI-ZCFIWIBFSA-N
PubChem
ClinicalTrials.gov
PubMed
Clinical Development by Virus
5
Human immunodeficiency virus 2
HIV-2
Target: Viral RT
FDA approved
Preclinical
Phase 2
positive
Phase 3
positive
Approved
FDA
China
Russia
Phase 3 ref (Ref)
Approval ref: AntiviralDb
PubChem CID:464205
NCT02180438
Hepatitis B virus
HBV
Target: Viral RT
FDA approved
Preclinical
Phase 2
positive
Phase 3
positive
Approved
FDA
China
Russia
Phase 3 ref (Ref)
PubChem CID:464205
NCT02039362
Human immunodeficiency virus 1
HIV-1
Target: Viral RT
FDA approved
Preclinical
Phase 2
positive
Phase 3
positive
Approved
FDA
China
Russia
Phase 3 ref (Ref)
PubChem CID:464205
NCT03998176
Human alphaherpesvirus 2
HSV-2
Target: Viral DNA pol
Phase 3
Preclinical
Phase 2
negative
Phase 3
Approved
Phase 2 ref (PMID:26044291)
Phase 3 ref (Ref)
NCT01386294
Severe acute respiratory syndrome-related coronavirus
SARS-CoV-2
Target: Viral RNA pol
Phase 2
Preclinical
Phase 2
Phase 3
Approved
NCT04812496