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Adefovir dipivoxil

Viral DNA chain termination

2D Structure

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3D Structure

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Chemical Identifiers

CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C(N=CN=C21)N)OCOC(=O)C(C)(C)C
WOZSCQDILHKSGG-UHFFFAOYSA-N
DrugBankClinicalTrials.govPubMed

Clinical Development by Virus4

Hepatitis B virus
HBV
Target: Viral RNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) DB00718
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref (kegg.jp) Approval ref (pmda.go.jp)
Cowpox virus
CPXV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:12821467
Vaccinia virus
VACV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:12821467