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Nelfinavir

HIV protease inhibitor · Inhibitor of lytic egress

2D Structure

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3D Structure

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Chemical Identifiers

CC1=C(C=CC=C1O)C(=O)NC(CSC2=CC=CC=C2)C(CN3CC4CCCCC4CC3C(=O)NC(C)(C)C)O
QAGYKUNXZHXKMR-HKWSIXNMSA-N
PubChemDrugBankClinicalTrials.govPubMed

Clinical Development by Virus15

Human immunodeficiency virus 1
HIV-1
Target: Viral protease
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Phase 3 ref (accessdata.fda.gov) Approval ref: AntiviralDbApproval ref (pmda.go.jp) PubChem CID:64143 DB00220 NCT00246610
Human gammaherpesvirus 8
KSHV
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:21402841
Human mastadenovirus B
HAdV-14
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:32601166
Human mastadenovirus C
HAdV-1
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:32601166
Human mastadenovirus C
HAdV-2
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:32601166
Human mastadenovirus C
HAdV-5
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:32601166
Human mastadenovirus C
HAdV-6
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:32601166
Chikungunya virus
CHIKV
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) Ref
Dengue virus
DENV-2
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) Ref
Influenza A virus
FLUAV
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:21620431
Hepacivirus C
HCV
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:19302339
Human alphaherpesvirus 1
HSV-1
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:24574416
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:15144898
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:33060595
Indiana vesiculovirus
VSV
Target: Unknown
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:21620431