RaDVaC Antiviral Database — Drugs, Trials, and Approvals Across All Viruses

2D Structure

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3D Structure

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Chemical Identifiers

SMILES:

CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O

InChI Key:

FBOZXECLQNJBKD-ZDUSSCGKSA-N

ClinicalTrials.gov PubMed

Clinical Development by Virus3

Human immunodeficiency virus 1

HIV-1

Phase 2

Preclinical

Phase 2negative

Phase 3

Approved

Phase 2 ref (PMID:39287554)

Severe acute respiratory syndrome-related coronavirus

SARS-CoV-2

Target: Human DHFR

Phase 2

Preclinical

Phase 2

Phase 3

Approved

ZIKV

Target: Human DHFR

Preclinical

Preclinical

Phase 2

Phase 3

Approved