RaDVaC Data Explorer
Antiviral database
Virus Taxonomy
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Adefovir
Inhibits viral DNA synthesis
2D Structure
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3D Structure
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Chemical Identifiers
SMILES:
C1=NC(=C2C(=N1)N(C=N2)CCOCP(=O)(O)O)N
InChI Key:
SUPKOOSCJHTBAH-UHFFFAOYSA-N
ClinicalTrials.gov
PubMed
Clinical Development by Virus
6
Hepatitis B virus
HBV
Target: DNA polymerase
FDA approved
Preclinical
Phase 2
positive
Phase 3
positive
Approved
FDA
Approval ref: AntiviralDb
Human immunodeficiency virus 1
HIV-1
Target: Viral RT
Phase 2
Preclinical
Phase 2
Phase 3
Approved
PMID:10682155
Hepatitis delta virus
HDV
Target: Viral RT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:23433964
Kappapapillomavirus 2
CRPV
Target: Viral RT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:11114415
Influenza A virus
FLUAV
Target: Viral RT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:7847879
Human alphaherpesvirus 1
HSV-1
Target: Viral RT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:2719463