Human mastadenovirus C
| Azacitidine | HAdV-5 | Nucleoside analog; DNA methyl transferase inhibitor | Preclinical | — | Viral DNA pol | |
| Cidofovir | HAdV-5 | Viral DNA polymerase inhibitor | Preclinical | — | Viral DNA pol | |
| Filociclovir | HAdV-5 | Dual DNA polymerase/kinase inhibitor; Nucleoside analog | Preclinical | — | Viral DNA pol | |
| Flavopiridol | HAdV-5 | CDK inhibitor | Preclinical | — | Human PTK | |
| Ingavirin | HAdV-5 | Unknown | Approved (other) | Russia | Unknown | |
| Inosine (Inosine pranobex) | HAdV-5 | Stimulates cell-mediated immune response | Preclinical | — | Viral DNA pol | |
| Ivermectin | HAdV-5 | Importin-mediated nuclear import inhibitor | Preclinical | — | Human importin | |
| Nelfinavir | HAdV-5 | Inhibitor of lytic egress | Approved (other) | Japan | Unknown | |
| Stavudine | HAdV-5 | Inhibition of viral RT | Approved (other) | JapanRussia | Viral DNA pol | |
| Valganciclovir | HAdV-5 | Destabilization of DNA | Approved (other) | Japan | Viral DNA pol | |
| Valproic Acid | HAdV-5 | HDAC inhibitor | Preclinical | — | Human HDAC | |
| Verdinexor | HAdV-5 | Nuclear export inhibitor | Preclinical | — | Human exportin |