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Valganciclovir

Destabilization of DNA

2D Structure

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3D Structure

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Chemical Identifiers

CC(C)C(C(=O)OCC(CO)OCN1C=NC2=C1N=C(NC2=O)N)N
WPVFJKSGQUFQAP-GKAPJAKFSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus4

Human cytomegalovirus (HCMV)
HCMV
Target: DNA polymerase UL54
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChinaRussia
Approval ref: AntiviralDbApproval ref (kegg.jp) Approval ref (pmda.go.jp)
Human betaherpesvirus 5
CMV
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChinaRussia
Approval ref (kegg.jp) Approval ref (pmda.go.jp) DB01610
Human gammaherpesvirus 8
KSHV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:32297410
Human mastadenovirus C
HAdV-5
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:25807051