Flaviviridae · Orthoflavivirus
| Anisomycin | JEV | DNA synthesis inhibitor | Preclinical | — | Human ribosome | |
| Azauridine | JEV | Nucleoside analog | Preclinical | — | Viral RNA pol | |
| Chlorpromazine | JEV | Inhibits assembly of clathrin-coated pits at the plasma membrane | Preclinical | — | Human (multiple) | |
| Eflornithine | JEV | Enzyme-activated; irreversible inhibitor of ornithine decarboxylase | Preclinical | — | Human ODC | |
| Etanercept | JEV | Unknown | Preclinical | — | Human TNF | |
| Galidesivir | JEV | RNA-dependent RNA polymerase (RdRp) inhibitor | Preclinical | — | Viral RNA pol | |
| Glycyrrhizin | JEV | 0 | Preclinical | — | Human TNF | |
| Luteolin | JEV | Unknown | Preclinical | — | Unknown | |
| Manidipine | JEV | Calcium channel blocker | Preclinical | — | Human ion channel | |
| Niclosamide | JEV | — | Preclinical | — | Human (multiple) | |
| Nitazoxanide | JEV | Pyruvate inhibitor | Preclinical | — | Human pyruvate synthase | |
| Novobiocin | JEV | Bacterial DNA gyrase inhibitor (targeting GyrB) | Preclinical | — | Unknown | |
| Ribavirin | JEV | Nucleoside inhibitor; Guanosine (ribonucleic) analog | Approved (other) | Japan | Viral RNA pol |