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Mycophenolic acid

Inosine monophosphate dehydrogenase inhibitor · Inhibition of Viral Genome Replication

2D Structure

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3D Structure

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Chemical Identifiers

CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
HPNSFSBZBAHARI-RUDMXATFSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus18

Human polyomavirus 1
BKV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
NCT01624948
Rubivirus rubellae
RuV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27468950
Chikungunya virus
CHIKV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:21070810
Dengue virus
DENV-2
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:12504563
Influenza A virus
FLUAV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:31941776
Human coronavirus NL63
HCoV-NL63
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30918074
Betacoronavirus 1
HCoV-OC43
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30918074
Hepacivirus C
HCV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30211024
Argentinian mammarenavirus
JUNV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:31302150
Lassa mammarenavirus
LASV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:31302150
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:31302150
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30918074
Norwalk virus
NoV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:28807916
Ross River virus
RRV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:29698664
Human orthopneumovirus
RSV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:28775087
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:32579258
Zika virus
ZIKV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27476412
Lujo mammarenavirus
LUJV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:34203149