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Chloroquine

Antimalaria agent; chemo/radio sensitizer · Antimalaria agentchemo/radio sensitizer

2D Structure

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3D Structure

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Chemical Identifiers

CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl
WHTVZRBIWZFKQO-UHFFFAOYSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus14

Phase 3
Preclinical
Phase 2negative
Phase 3negative
Approved
Phase 2 ref (PMID:33682640) Phase 3 ref (PMID:33907251) NCT04331600 PMID:32020029
Hepacivirus C
HCV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
NCT02058173
Human immunodeficiency virus 1
HIV-1
Target: Human (multiple)
Phase 3
Preclinical
Phase 2
Phase 3
Approved
NCT00308620
Chikungunya virus
CHIKV
Target: Human (multiple)
Phase 3
Preclinical
Phase 2
Phase 3
Approved
PMID:29772762 NCT00391313
Dengue virus
DENV
Target: Human (multiple)
Phase 2
Preclinical
Phase 2
Phase 3
Approved
PMID:25664975 NCT00849602
Influenza A virus
FLUAV
Target: Human (multiple)
Phase 2
Preclinical
Phase 2
Phase 3
Approved
NCT01078779
Zaire ebolavirus
EBOV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27622822
Enterovirus A
EV-A71
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:29175128
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:25796972
Betacoronavirus 1
HCoV-OC43
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27381385
Human gammaherpesvirus 8
KSHV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27521848
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24841273
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:14592603
Zika virus
ZIKV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27916837