Crimean-Congo hemorrhagic fever orthonairovirus
| Chloroquine | CCHFV | Antimalaria agent; chemo/radio sensitizer | Preclinical | — | Human (multiple) | |
| Chlorpromazine | CCHFV | Inhibits assembly of clathrin-coated pits at the plasma membrane | Preclinical | — | Human (multiple) | |
| CR-1-31-B | CCHFV | Prevents mRNA translation | Preclinical | — | Human ATPase | |
| Favipiravir | CCHFV | Viral RNA polymerase inhibitor | Approved (other) | Japan | Viral RNA pol | |
| Silvestrol | CCHFV | RNA helicase inhibitor | Preclinical | — | Human EIF4A | |
| Taribavirin | CCHFV | Human (multiple) | Preclinical | — | Viral RNA pol |