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Eflornithine

Enzyme-activated; irreversible inhibitor of ornithine decarboxylase

2D Structure

Could not render structureView on PubChem

3D Structure

No structure available on PubChemSearch PubChem

Chemical Identifiers

C(CC(C(F)F)(C(=O)O)N)CN
VLCYCQAOQCDTCN-UHFFFAOYSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus9

Chikungunya virus
CHIKV
Target: Human ODC
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27535047
Human betaherpesvirus 5
CMV
Target: Human ODC
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:6283366
Enterovirus B
CVB-3
Target: Human ODC
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27535047
Human alphaherpesvirus 1
HSV-1
Target: Human ODC
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:12569563
Japanese encephalitis virus
JEV
Target: Human ODC
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27535049
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27535050
Sindbis virus
SINV
Target: Human ODC
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27535047
Indiana vesiculovirus
VSV
Target: Human ODC
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27535047
Zika virus
ZIKV
Target: Human ODC
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27535047