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Berberine

AMP-activated protein kinase (AMPK) activator

2D Structure

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3D Structure

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Chemical Identifiers

COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC
YBHILYKTIRIUTE-UHFFFAOYSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus13

Chikungunya virus
CHIKV
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:26752081
Human betaherpesvirus 5
CMV
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30738836
Influenza A virus
FLUAV
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:21683808
Hepacivirus C
HCV
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30668413
Enterovirus A
EV-A71
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:28081706
Enterovirus B
CVB-3
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:28341822
Human immunodeficiency virus 1
HIV-1
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:21295891
Alphapapillomavirus 9
HPV-16
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:21496227
Human alphaherpesvirus 1
HSV-1
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24913175
Human orthopneumovirus
RSV
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:25939536
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:33670363
Sindbis virus
SINV
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:26752081
Zika virus
ZIKV
Target: Unknown
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30641880