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Merimepodib

IMPDH inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

COC1=C(C=CC(=C1)NC(=O)NC2=CC=CC(=C2)CNC(=O)OC3CCOC3)C4=CN=CO4
JBPUGFODGPKTDW-SFHVURJKSA-N

Clinical Development by Virus13

Hepacivirus C
HCV
Target: Human IMPDH
Phase 2
Preclinical
Phase 2
Phase 3
Approved
Chikungunya virus
CHIKV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Human betaherpesvirus 5
CMV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Zaire ebolavirus
EBOV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Cardiovirus A
EMCV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Hepatitis B virus
HBV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Human respirovirus 3
HPIV-3
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Human alphaherpesvirus 1
HSV-1
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Argentinian mammarenavirus
JUNV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Lassa mammarenavirus
LASV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Human orthopneumovirus
RSV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Zika virus
ZIKV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved