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Memantine

N-methyl-D-aspartate glutamate receptor antagonist

2D Structure

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3D Structure

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Chemical Identifiers

CC12CC3CC(C1)(CC(C3)(C2)N)C
BUGYDGFZZOZRHP-UHFFFAOYSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus5

Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:34696509
Human immunodeficiency virus 1
HIV-1
Target: Human ion channel
Phase 2
Preclinical
Phase 2
Phase 3
Approved
PMID:1707644 NCT00000867
Betacoronavirus 1
HCoV-OC43
Target: Human ion channel
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24227863
Zika virus
ZIKV
Target: Human ion channel
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:28442607
Influenza A virus
FLUAV
Target: Human ion channel
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:9588841