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Homoharringtonine

Protein translation inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

CC(C)(CCCC(CC(=O)OC)(C(=O)OC1C2C3=CC4=C(C=C3CCN5C2(CCC5)C=C1OC)OCO4)O)…
HYFHYPWGAURHIV-JFIAXGOJSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus6

Enterovirus B
ECHOV-1
Target: Human ribosome
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:31635418
Hepatitis B virus
HBV
Target: Human ribosome
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:17458779
Human alphaherpesvirus 1
HSV-1
Target: Human ribosome
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30388805
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:25451075
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:32251767
Human alphaherpesvirus 3
VZV
Target: Human ribosome
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30456755