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Amodiaquine

Methyltransferase inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O
OVCDSSHSILBFBN-UHFFFAOYSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus15

Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:33941899
Zika virus
ZIKV
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:28736217
Dengue virus
DENV-2
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24680954
Zaire ebolavirus
EBOV
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30395872
Hepacivirus C
HCV
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
Human alphaherpesvirus 1
HSV-1
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
Lassa mammarenavirus
LASV
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30700611
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24841273
Rabies lyssavirus
RABV
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
Ross River virus
RRV
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24841273
Sindbis virus
SINV
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
Indiana vesiculovirus
VSV
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609
West Nile virus
WNV
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24680954
Yellow fever virus
YFV
Target: Human HNMT
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30791609