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Vidarabine

Viral DNA synthesis inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N
OIRDTQYFTABQOQ-UHTZMRCNSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus13

Herpes simplex virus (HSV)
HSV
Target: DNA polymerase UL30
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref: AntiviralDbApproval ref (pmda.go.jp)
Human alphaherpesvirus 3
VZV
Target: DNA polymerase
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref: AntiviralDbApproval ref (pmda.go.jp) DB00194
Human alphaherpesvirus 1
HSV-1
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref (pmda.go.jp) DB00194
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref (pmda.go.jp)
Human alphaherpesvirus 2
HSV-2
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref (pmda.go.jp) DB00194
Human papillomavirus
HPV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:12883720
Human adenovirus
HAdV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:9313882
Human polyomavirus 1
BKV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:1651795
Enterovirus B
CVB-4
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:9597914
Powassan virus
POWV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:6297420
PyV
PyV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:9313882
Rabies lyssavirus
RABV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:1245759
Variola virus
VARV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:302323