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Remdesivir

Viral RNA polymerase inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

CCC(CC)COC(=O)C(C)NP(=O)(OCC1C(C(C(O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=…
RWWYLEGWBNMMLJ-YSOARWBDSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus15

Zaire ebolavirus
EBOV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2positive
Phase 3negative
Approved
Japan
Phase 3 ref (nejm.org) Approval ref (kegg.jp) Approval ref (pmda.go.jp) NCT03719586
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChinaRussia
Approval ref: AntiviralDbApproval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:32251767
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28659436
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:29511076
Human coronavirus 229E
HCoV-229E
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:31233808
Betacoronavirus 1
HCoV-OC43
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:31233808
Hepacivirus C
HCV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28262699
Orthohepevirus A
HEV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28262699
Human metapneumovirus
HMPV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28262699
Argentinian mammarenavirus
JUNV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28262699
Lassa mammarenavirus
LASV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28262699
Marburg marburgvirus
MARV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28262699
Nipah henipavirus
NiV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:29425244
Human orthopneumovirus
RSV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28262699
Tick-borne encephalitis virus
TBEV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:28262699