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Podofilox

2D Structure

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3D Structure

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Chemical Identifiers

COC1=CC(=CC(=C1OC)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)O
YJGVMLPVUAXIQN-XVVDYKMHSA-N

Clinical Development by Virus6

Human papillomavirus
HPV
Target: Human topoisomerase
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDA
Approval ref: AntiviralDbDB01179
Molluscum contagiosum virus
MCV
Target: Human topoisomerase
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Human betaherpesvirus 5
CMV
Target: Human topoisomerase
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Influenza A virus
FLUAV
Target: Human topoisomerase
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Human alphaherpesvirus 1
HSV-1
Target: Human topoisomerase
Preclinical
Preclinical
Phase 2
Phase 3
Approved
Indiana vesiculovirus
VSV
Target: Human topoisomerase
Preclinical
Preclinical
Phase 2
Phase 3
Approved