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Penciclovir

Inhibits viral DNA synthesis

2D Structure

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3D Structure

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Chemical Identifiers

C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)N
JNTOCHDNEULJHD-UHFFFAOYSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus4

Herpes simplex virus (HSV)
HSV
Target: DNA polymerase UL30
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDA
Approval ref: AntiviralDb
Human alphaherpesvirus 1
HSV-1
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDA
DB00299
Human alphaherpesvirus 2
HSV-2
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDA
DB00299
Hepatitis B virus
HBV
Target: Viral DNA pol
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:10760047