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Etravirine

Inhibition of viral RT

2D Structure

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3D Structure

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Chemical Identifiers

CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N
PYGWGZALEOIKDF-UHFFFAOYSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus3

FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref: AntiviralDbApproval ref (kegg.jp) Approval ref (pmda.go.jp)
Human immunodeficiency virus 1
HIV-1
Target: Viral RT
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) DB06414
Zika virus
ZIKV
Target: Viral RNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (kegg.jp) Approval ref (pmda.go.jp) PMID:31653397