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Antiviral database
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Dyphillin
vacuolar ATPase inhibitors
2D Structure
Could not render structure
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3D Structure
No structure available on PubChem
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Chemical Identifiers
SMILES:
CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(CO)O
InChI Key:
KSCFJBIXMNOVSH-UHFFFAOYSA-N
ClinicalTrials.gov
PubMed
Clinical Development by Virus
5
Influenza A virus
FLUAV
Target: Human vATPase
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30587980
Zaire ebolavirus
EBOV
Target: Human vATPase
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30335906
Human immunodeficiency virus 1
HIV-1
Target: Human vATPase
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:29328465
Severe acute respiratory syndrome-related coronavirus
SARS-CoV-2
Target: Human vATPase
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:33668694
Zika virus
ZIKV
Target: Human vATPase
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:31501074