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AVN-944

IMPDH inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

CCC(CC#N)OC(=O)NC(C)C1=CC(=CC=C1)NC(=O)NC2=CC(=C(C=C2)C3=CN=CO3)OC
GYCPCOJTCINIFZ-OXJNMPFZSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus8

Human betaherpesvirus 5
CMV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:10722482
Cardiovirus A
EMCV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:10722482
Hepatitis B virus
HBV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:10722482
Human respirovirus 3
HPIV-3
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:10722482
Human alphaherpesvirus 1
HSV-1
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:10722482
Human orthopneumovirus
RSV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:10722482
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:10722482
Lujo mammarenavirus
LUJV
Target: Human IMPDH
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:34203149