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Tenofovir alafenamide

2D Structure

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3D Structure

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Chemical Identifiers

CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3
LDEKQSIMHVQZJK-CAQYMETFSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus2

FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChina
Approval ref: AntiviralDbApproval ref (kegg.jp) Approval ref (pmda.go.jp)
Hepatitis B virus
HBV
Target: DNA polymerase
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapanChina
Approval ref: AntiviralDbApproval ref (kegg.jp) Approval ref (pmda.go.jp)