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Idoxuridine

Inhibits viral DNA synthesis

2D Structure

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3D Structure

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Chemical Identifiers

C1C(C(OC1N2C=C(C(=O)NC2=O)I)CO)O
XQFRJNBWHJMXHO-RRKCRQDMSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus10

Herpes simplex virus (HSV)
HSV
Target: DNA polymerase UL30
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref: AntiviralDbApproval ref (pmda.go.jp)
Human alphaherpesvirus 1
HSV-1
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref (pmda.go.jp) DB00249
Human alphaherpesvirus 2
HSV-2
Target: Viral DNA pol
FDA approved
Preclinical
Phase 2positive
Phase 3positive
Approved
FDAJapan
Approval ref (pmda.go.jp) DB00249
Alphapapillomavirus 10
HPV-6
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:2174190
Alphapapillomavirus 10
HPV-11
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:2174190
Alphapapillomavirus 9
HPV-16
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:2174190
Alphapapillomavirus 7
HPV-18
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:2174190
Orf virus
ORFV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:6539075
PyV
PyV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:14320955
Vaccinia virus
VACV
Target: Viral DNA pol
Approved (other)
Preclinical
Phase 2
Phase 3
Approved
Japan
Approval ref (pmda.go.jp) PMID:12183236