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Benztropine

Selective inhibition of dopamine transporters but it also presents affinity for histamine and muscarine receptors

2D Structure

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3D Structure

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Chemical Identifiers

CN1C2CCC1CC(C2)OC(C3=CC=CC=C3)C4=CC=CC=C4
GIJXKZJWITVLHI-PMOLBWCYSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus6

Zaire ebolavirus
EBOV
Target: Human CHRM1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:26202243
Hepacivirus C
HCV
Target: Human CHRM1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24709263
Marburg marburgvirus
MARV
Target: Human CHRM1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:26202243
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24841273
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:24841273
Lujo mammarenavirus
LUJV
Target: Human CHRM1
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:34203149