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Posaconazole

Inhibition of OSBP and ORP4; Inhibition of viral organelle formation

2D Structure

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3D Structure

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Chemical Identifiers

CCC(C(C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5CC(OC5…
RAGOYPUPXAKGKH-XAKZXMRKSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus6

Dengue virus
DENV-1
Target: Human lipid transfer protein
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:29981375
Dengue virus
DENV-2
Target: Human lipid transfer protein
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:29981375
Dengue virus
DENV-4
Target: Human lipid transfer protein
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:29981375
Zaire ebolavirus
EBOV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:27890675
Parechovirus A
HPEV-3
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:29155163
Zika virus
ZIKV
Target: Human (multiple)
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:29981375