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Apilimod

PIKfyve kinase inhibitor

2D Structure

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3D Structure

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Chemical Identifiers

CC1=CC(=CC=C1)C=NNC2=CC(=NC(=N2)OCCC3=CC=CC=N3)N4CCOCC4
HSKAZIJJKRAJAV-KOEQRZSOSA-N
ClinicalTrials.govPubMed

Clinical Development by Virus7

Zaire ebolavirus
EBOV
Target: Human PTK
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:28403145
Lassa mammarenavirus
LASV
Target: Human PTK
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:30700611
Marburg marburgvirus
MARV
Target: Human PTK
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:28403145
African swine fever virus
ASFV
Target: Human PTK
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:33249093
Human coronavirus 229E
HCoV-229E
Target: Human PTK
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:33249093
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:33249093
Lujo mammarenavirus
LUJV
Target: Human PTK
Preclinical
Preclinical
Phase 2
Phase 3
Approved
PMID:34203149