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Cervarix

Virus-like particle vaccine · VDDBV0136

Target & Classification

HPVHuman papillomavirus
Virus-like particle vaccine
Recurrent Respiratory Papillomatosis; Cervical Intraepithelial Neoplasia Grade 2; 3; Unresectable Head and Neck Squamous Cell Carcinoma; Metastatic Head and Neck Cancer; Recurrent Head and Neck Cancer; HPV-Related Squamous Cell Carcinoma; Cervical Cancer; Healthy; Human Papilloma Virus; Cervical Intraepithelial Neoplasia; Papillomavirus Infection; Human Papillomavirus (HPV) Infection; Human Papillomavirus Infection Leading to Cervical Cancer; Infections, Papillomavirus; Infections, Papillomavirus; Papillomavirus Vaccines; Papillomavirus Type 16; 18 Infection; Cervical Intraepithelial Neoplasia; Locally Advanced Head and Neck Cancer; Squamous Cell Carcinoma of the Oropharynx; HPV; HPV Positive Oropharyngeal Squamous Cell Carcinoma; HPV Infection; CIN1; Cancer of Head and Neck; Cancer of Cervix; Cancer of Anus; Squamous Cell Carcinoma of the Head and Neck; Squamous Cell Head and Neck Carcinoma; Human Papillomavirus-Related Cervical Squamous Cell Carcinoma; Non-small Cell Lung Cancer; Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC (American Joint Committee on Cancer) v8; Human Papillomavirus Infection; HPV Infection; Genital Human Papilloma Virus Infection; AIN; HIV; Anal Cancer; HIV Infections; Cervical Cancer; Cervical Precancerous Lesions; Cervical Intraepithelial Neoplasia; Cervical Cancer; Cervical Neoplasm; Cervical Dysplasia; Human Papillomavirus; Human Papillomavirus
ApprovedPhase 4 reached

Clinical Development

Phase 1
Phase 2
Phase 3
Approved

Clinical Trials54

Note: 1 additional source trial listed this vaccine in studies of unrelated viruses (e.g. as a comparator, adjunct, or in coadministration trials with other vaccines). Those trials are not shown here.

NCT IDPhaseDisease / Condition
NCT03747770 —Recurrent Respiratory Papillomatosis
NCT02834637 Phase 3Recurrent Respiratory Papillomatosis
NCT01717118 ApprovedCervical Intraepithelial Neoplasia Grade 2; 3
NCT02296255 ApprovedUnresectable Head and Neck Squamous Cell Carcinoma; Metastatic Head and Neck Cancer; Recurrent Head and Neck Cancer
NCT00316706 Phase 3HPV-Related Squamous Cell Carcinoma
NCT00481767 Phase 3Cervical Cancer
NCT00730847 ApprovedHealthy
NCT00196937 Phase 3Human Papilloma Virus
NCT00811798 Phase 3Healthy
NCT00552279 Phase 3Cervical Cancer
NCT00309166 Phase 2Cervical Intraepithelial Neoplasia; Papillomavirus Infection
NCT00689741 Phase 2Human Papillomavirus (HPV) Infection
NCT00586339 Phase 2Human Papillomavirus Infection Leading to Cervical Cancer
NCT01627561 Phase 3Infections, Papillomavirus
NCT00541970 Phase 1Infections, Papillomavirus
NCT01418937 Phase 3Infections, Papillomavirus
NCT00996125 Phase 3Infections, Papillomavirus
NCT00546078 Phase 2Infections, Papillomavirus
NCT00492544 Phase 3Infections, Papillomavirus
NCT00799825 Phase 3Infections, Papillomavirus
NCT01190189 Phase 3Infections, Papillomavirus
NCT01249365 Phase 3Infections, Papillomavirus
NCT01277042 Phase 3Infections, Papillomavirus
NCT00549900 Phase 1Infections, Papillomavirus; Papillomavirus Vaccines
NCT00849381 Phase 3Infections, Papillomavirus; Papillomavirus Vaccines
NCT00294047 Phase 3Infections, Papillomavirus; Papillomavirus Vaccines
NCT00359619 Phase 2Infections, Papillomavirus; Papillomavirus Vaccines
NCT00250276 Phase 3Papillomavirus Type 16; 18 Infection; Cervical Intraepithelial Neoplasia
NCT00423046 Phase 3Infections, Papillomavirus
NCT00337818 Phase 3Infections, Papillomavirus; Papillomavirus Vaccines
NCT01381575 Phase 3Infections, Papillomavirus
NCT01031069 ApprovedInfections, Papillomavirus
NCT00316693 Phase 2Infections, Papillomavirus
NCT00485732 Phase 3Infections, Papillomavirus
NCT00693966 Phase 2Locally Advanced Head and Neck Cancer
NCT00693615 Phase 2Squamous Cell Carcinoma of the Oropharynx; HPV
NCT00456807 Phase 3HPV Positive Oropharyngeal Squamous Cell Carcinoma
NCT00345878 Phase 3HPV Infection; CIN1
NCT00344032 Phase 3Cancer of Head and Neck; Cancer of Cervix; Cancer of Anus
NCT00637195 Phase 3Squamous Cell Carcinoma of the Head and Neck
NCT03629886 ApprovedSquamous Cell Head and Neck Carcinoma
NCT00779766 Phase 3Squamous Cell Carcinoma of the Head and Neck
NCT00652938 Phase 3Human Papillomavirus-Related Cervical Squamous Cell Carcinoma; Non-small Cell Lung Cancer
NCT00369824 Phase 3Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC (American Joint Committee on Cancer) v8
NCT01082861 ApprovedHuman Papillomavirus Infection
NCT00534638 ApprovedHPV Infection
NCT03105856 ApprovedGenital Human Papilloma Virus Infection
NCT00956553 ApprovedAIN; HIV
NCT01914367 ApprovedAnal Cancer; HIV Infections
NCT01462357 Phase 3Cervical Cancer
NCT02082639 Phase 3Cervical Cancer; Cervical Precancerous Lesions
NCT00122681 Phase 3Cervical Intraepithelial Neoplasia; Cervical Cancer; Cervical Neoplasm; Cervical Dysplasia; Human Papillomavirus
NCT00578227 Phase 3Human Papillomavirus
NCT00128661 Phase 3Human Papillomavirus Infection